Histone octamer (transglutaminase) - Revision history

Bernadett at 11:42, 10 March 2015

2015-03-10T11:42:25Z

WikiSysop at 13:52, 3 September 2007

2007-09-03T13:52:28Z

WikiSysop: New page: {| class="toccolours" border="1" style="float: left; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;" ! {{infobox header}}| '''{{PAGENAME}}''' |- | align="center" colspan="2...

2007-09-03T13:31:11Z

New page: {| class="toccolours" border="1" style="float: left; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;" ! {{infobox header}}| '''{{PAGENAME}}''' |- | align="center" colspan="2...

New page

{| class="toccolours" border="1" style="float: left; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;"
! {{infobox header}}| '''{{PAGENAME}}'''
|-
| align="center" colspan="2" bgcolor="#ffffff" | [[Image:HistoneH2A.JPG|200px|{{PAGENAME}}]] [[Image:HistoneH2B.JPG|200px|{{PAGENAME}}]] [[Image:HistoneH3.JPG|200px|{{PAGENAME}}]] [[Image:HistoneH4.JPG|200px|{{PAGENAME}}]]
|-
| Substrate peptide name
| {{PAGENAME}}
|-
| Synonyms
| Core histone
|-
| Determination type
| In situ/In vitro
|-
| Source
| Homo sapiens
Gallus gallus
|-
| Subcellular localization
| Nuclear
|-
| Swissprot ID
| [http://au.expasy.org/uniprot/P08865 P08865]
[http://au.expasy.org/uniprot/P08865 P08865]
[http://au.expasy.org/uniprot/P08865 P08865]
[http://au.expasy.org/uniprot/P08865 P08865]
|-
| Reactive glutamines
| [[TG2 reactive residues (Histone H2A)|H2A – '''Q24, Q104, Q112''']]

[[TG2 reactive residues (Histone H2B)|H2B – '''Q95''']], ''Q22''

[[TG2 reactive residues (Histone H3)|H3 – '''Q125''']], '''''Q5, Q19'''''

[[TG2 reactive residues (Histone H4)|H4 – '''Q27, Q93''']]

|-
| Reactive lysines
| [[TG2 reactive residues (Histone H2B)|H2B - '''K116''']], K125
|-
| Substrate sequence
| H2A – KVTIA''Q''GGVLPNI''Q''AVLLP

H2B – TSREI''Q''TAVRL

H2B - VESEG''K''AVTKYTSS''K''

H3 - ARTK''Q''TARKS

H3 - KAPRK''Q''L

H3 - MPKDI''Q''LARRI

H4 – LKR''Q''GRTLY

|-
| Structure
| [http://www.rcsb.org/pdb/explore/explore.do?structureId=1TZY 1TZY]
|-
| Surface accessibility
| [http://gibk21.bse.kyutech.ac.jp/asaview/all/2tzyA.pdf ASAView] pdf
|-
| Disorder prediction
| [http://iupred.enzim.hu/index.html IUPred]
|-
| Reference
| [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=8702540&dopt=Abstract PMID:8702540]
[http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=12054678&dopt=Abstract PMID:12054678]
|-
| Notes
| *Residues in bold are TG2 substrates in free core histones; residues in italics (Q22, Q5 and Q19) serve as TG2 substrates in nucleosomes.

Q122 is substrate only at certain temperature

|-
| {{infobox header}} |
|-
|}

[[Category:Tissue transglutaminase|*]]

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-! {{infobox header}}| '''{{PAGENAME}}'''
+! {infobox header}| '''{{PAGENAME}}'''
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 | Substrate peptide name
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 [[Category:Tissue transglutaminase|*]]

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 |-
 | Swissprot ID
-| [http://au.expasy.org/uniprot/P08865 P08865]
+| [http://au.expasy.org/uniprot/P04908 P04908 ]
-[http://au.expasy.org/uniprot/P08865 P08865]
+[http://au.expasy.org/uniprot/P02278 P02278 ]
-[http://au.expasy.org/uniprot/P08865 P08865]
+[http://au.expasy.org/uniprot/P02304 P02304 ]
-[http://au.expasy.org/uniprot/P08865 P08865]
+[http://au.expasy.org/uniprot/Q16695 Q16695 ]
 |-
 | Reactive glutamines