Difference between revisions of "Histone octamer (transglutaminase)"

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| Swissprot ID
 
| Swissprot ID
| [http://au.expasy.org/uniprot/P08865 P08865]
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| [http://au.expasy.org/uniprot/P04908 P04908 ]
[http://au.expasy.org/uniprot/P08865 P08865]
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[http://au.expasy.org/uniprot/P02278 P02278 ]
[http://au.expasy.org/uniprot/P08865 P08865]
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[http://au.expasy.org/uniprot/P02304 P02304 ]
[http://au.expasy.org/uniprot/P08865 P08865]
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[http://au.expasy.org/uniprot/Q16695 Q16695 ]
 
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| Reactive glutamines
 
| Reactive glutamines

Revision as of 13:52, 3 September 2007

Template:Infobox header| Histone octamer (transglutaminase)
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Histone octamer (transglutaminase) Histone octamer (transglutaminase) Histone octamer (transglutaminase)
Substrate peptide name Histone octamer (transglutaminase)
Synonyms Core histone
Determination type In situ/In vitro
Source Homo sapiens

Gallus gallus

Subcellular localization Nuclear
Swissprot ID P04908

P02278 P02304 Q16695

Reactive glutamines H2A – Q24, Q104, Q112

H2B – Q95, Q22

H3 – Q125, Q5, Q19

H4 – Q27, Q93

Reactive lysines H2B - K116, K125
Substrate sequence H2A – KVTIAQGGVLPNIQAVLLP

H2B – TSREIQTAVRL

H2B - VESEGKAVTKYTSSK

H3 - ARTKQTARKS

H3 - KAPRKQL

H3 - MPKDIQLARRI

H4 – LKRQGRTLY

Structure 1TZY
Surface accessibility ASAView pdf
Disorder prediction IUPred
Reference PMID:8702540

PMID:12054678

Notes *Residues in bold are TG2 substrates in free core histones; residues in italics (Q22, Q5 and Q19) serve as TG2 substrates in nucleosomes.

Q122 is substrate only at certain temperature

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