Difference between revisions of "Glyceraldehyde-3-phosphate dehydrogenase"

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! {{infobox header}}| '''{{PAGENAME}}'''  
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! {infobox header}| '''{{PAGENAME}}'''  
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| align="center" colspan="2" bgcolor="#ffffff" | [[Image:{{PAGENAME}}.png|200px|{{PAGENAME}}]]
 
 
|-
 
|-
 
| Substrate peptide name
 
| Substrate peptide name
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|-
 
|-
 
| Synonyms
 
| Synonyms
| -
+
| GAPDH
 
|-
 
|-
 
| Determination type
 
| Determination type
| In situ
+
| In vitro
 
|-
 
|-
 
| Source
 
| Source
| Homo sapiens
+
| Oryctolagus cuniculus (rabbit)
 
|-
 
|-
 
| Subcellular localization
 
| Subcellular localization
| Cytoskeleton
+
| Mainly cytosolic associated to cytoskeleton and membranes
 +
Nucleus
 
|-
 
|-
 
| Swissprot ID
 
| Swissprot ID
| [http://au.expasy.org/uniprot/P08865 P08865]
+
| [http://au.expasy.org/uniprot/P46406 P46406]
 
|-
 
|-
 
| Reactive glutamines
 
| Reactive glutamines
| [[Q41 (Actin)|Q41]]
+
| -
 
|-
 
|-
 
| Reactive lysines
 
| Reactive lysines
| Not determined yet
+
| [[TG2 reactive residues (GAPDH)|K191, K268, K331]]
 
|-
 
|-
 
| Substrate sequence
 
| Substrate sequence
| GRPRHQGVMVG
+
| DSPSG''K''LWRGG
 +
 
 +
SEGPL''K''GILGY
 +
 
 +
AHMAS''K''E
 +
 
 
|-
 
|-
 
| Structure
 
| Structure
| [http://www.rcsb.org/pdb/explore/explore.do?structureId=2BTF 2BTF]
+
| [http://www.rcsb.org/pdb/explore/explore.do?structureId=1J0X 1J0X]
 
|-
 
|-
 
| Surface accessibility
 
| Surface accessibility
| [http://gibk21.bse.kyutech.ac.jp/asaview/all/2btfA.pdf ASAView] pdf
+
| [http://gibk21.bse.kyutech.ac.jp/netasa/asaview/tmp/120891ext.pdf ASAView] pdf
 
|-
 
|-
 
| Disorder prediction
 
| Disorder prediction
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|-
 
|-
 
| Reference
 
| Reference
| [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=9252372&dopt=Abstract PMID:9252372]
+
| [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=11742130&dopt=Abstract PMID:11742130]
 
|-
 
|-
 
| Notes
 
| Notes
|  
+
| It's activity decreases upon crosslinking by TG2
 +
 
 
|-
 
|-
| {{infobox header}} |  
+
| {infobox header} |  
 
|-
 
|-
 
|}
 
|}
  
 
[[Category:Tissue transglutaminase|*]]
 
[[Category:Tissue transglutaminase|*]]

Latest revision as of 11:40, 10 March 2015

Glyceraldehyde-3-phosphate dehydrogenase
Substrate peptide name Glyceraldehyde-3-phosphate dehydrogenase
Synonyms GAPDH
Determination type In vitro
Source Oryctolagus cuniculus (rabbit)
Subcellular localization Mainly cytosolic associated to cytoskeleton and membranes

Nucleus

Swissprot ID P46406
Reactive glutamines -
Reactive lysines K191, K268, K331
Substrate sequence DSPSGKLWRGG

SEGPLKGILGY

AHMASKE

Structure 1J0X
Surface accessibility ASAView pdf
Disorder prediction IUPred
Reference PMID:11742130
Notes It's activity decreases upon crosslinking by TG2