Difference between revisions of "RhoA"
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| − | ! | + | ! {infobox header}| '''{{PAGENAME}}''' |
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| align="center" colspan="2" bgcolor="#ffffff" | [[Image:RhoA.JPG|200px|{{PAGENAME}}]] | | align="center" colspan="2" bgcolor="#ffffff" | [[Image:RhoA.JPG|200px|{{PAGENAME}}]] | ||
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| Q63 is deamidated/transamidated by TG2 | | Q63 is deamidated/transamidated by TG2 | ||
| − | The transamidated protein has increased binding affinity to ROCK-2. The deamidated form (by cytotoxic dermonecrotizing factor or BTX) has decreased GTPase activity. | + | The transamidated protein has increased binding affinity to ROCK-2. |
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| + | The deamidated form (by cytotoxic dermonecrotizing factor or BTX) has decreased GTPase activity. | ||
| + | |- | ||
| + | |Video | ||
| + | |{{#ev:dailymotion|19dSThNNq2NLtkXZ8|300}} | ||
|- | |- | ||
| − | | | + | | {infobox header} | |
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|} | |} | ||
[[Category:Tissue transglutaminase|*]] | [[Category:Tissue transglutaminase|*]] | ||
| + | [[Category:Deamidase|*]] | ||
Latest revision as of 11:54, 10 March 2015
| RhoA | |
|---|---|
| |
| Substrate peptide name | RhoA |
| Synonyms | - |
| Determination type | In situ/In vitro |
| Source | Homo sapiens |
| Subcellular localization | Cytoskeleton |
| Swissprot ID | P61586 |
| Reactive glutamines | Q52, Q63, Q136 |
| Reactive lysines | - |
| Substrate sequence | EVDGKQVELAL
WDTAGQEDYDR LAKMKQEPVKP |
| Structure | 1A2B |
| Surface accessibility | ASAView pdf
ASAView txt |
| Disorder prediction | IUPred |
| Reference | PMID:9593707 |
| Notes | Q63 is deamidated/transamidated by TG2
The transamidated protein has increased binding affinity to ROCK-2. The deamidated form (by cytotoxic dermonecrotizing factor or BTX) has decreased GTPase activity. |
| Video | 19dSThNNq2NLtkXZ8|300}} |
