Difference between revisions of "RhoA"
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The transamidated protein has increased binding affinity to ROCK-2. | The transamidated protein has increased binding affinity to ROCK-2. | ||
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The deamidated form (by cytotoxic dermonecrotizing factor or BTX) has decreased GTPase activity. | The deamidated form (by cytotoxic dermonecrotizing factor or BTX) has decreased GTPase activity. | ||
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Latest revision as of 11:54, 10 March 2015
RhoA | |
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Substrate peptide name | RhoA |
Synonyms | - |
Determination type | In situ/In vitro |
Source | Homo sapiens |
Subcellular localization | Cytoskeleton |
Swissprot ID | P61586 |
Reactive glutamines | Q52, Q63, Q136 |
Reactive lysines | - |
Substrate sequence | EVDGKQVELAL
WDTAGQEDYDR LAKMKQEPVKP |
Structure | 1A2B |
Surface accessibility | ASAView pdf
ASAView txt |
Disorder prediction | IUPred |
Reference | PMID:9593707 |
Notes | Q63 is deamidated/transamidated by TG2
The transamidated protein has increased binding affinity to ROCK-2. The deamidated form (by cytotoxic dermonecrotizing factor or BTX) has decreased GTPase activity. |
Video | 19dSThNNq2NLtkXZ8|300}} |