Difference between revisions of "S100A11 (TG2)"
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| Notes | | Notes | ||
− | | | + | |Transamidation by TG2 transforms S100A11 into a covalently bonded homodimer |
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+ | that acquires the capacity to signal through the p38 MAPK pathway, accelerate | ||
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+ | chondrocyte hypertrophy and matrix catabolism. | ||
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|Video | |Video | ||
− | |{{#ev: | + | |{{#ev:dailymotion|1qxapT72gvd7lkY0F|300}} |
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− | | | + | | {infobox header} | |
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[[Category:Tissue transglutaminase|*]] | [[Category:Tissue transglutaminase|*]] |
Latest revision as of 11:55, 10 March 2015
S100A11 (TG2) | |
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Substrate peptide name | S100A11 |
Synonyms | S100 calcium-binding protein A11
Calgizzarin |
Determination type | In situ/In vitro |
Source | Homo sapiens |
Subcellular localization | Cytosol
Keratinocyte cornified envelope |
Swissprot ID | P31949 |
Reactive glutamines | Q102 |
Reactive lysines | K3 |
Substrate sequence | KAVPSQKRT
MASKISSPT |
Structure | 1QLS |
Surface accessibility | ASAView pdf
ASAView txt |
Disorder prediction | IUPred |
Reference | PMID:9446578 |
Notes | Transamidation by TG2 transforms S100A11 into a covalently bonded homodimer
that acquires the capacity to signal through the p38 MAPK pathway, accelerate chondrocyte hypertrophy and matrix catabolism. |
Video | 1qxapT72gvd7lkY0F|300}} |