Difference between revisions of "Tau protein"
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| Swissprot ID | | Swissprot ID | ||
| − | | [http://au.expasy.org/uniprot/ | + | | [http://au.expasy.org/uniprot/P10636 P10636 ] |
|- | |- | ||
| Reactive glutamines | | Reactive glutamines | ||
| − | | | + | | Q6, Q88, Q124, Q244, Q276, Q288, Q351, Q424 |
|- | |- | ||
| Reactive lysines | | Reactive lysines | ||
| − | | | + | | K24, K163, K174, K180, K190, K225, K234, K240, K383, K385 |
|- | |- | ||
| Substrate sequence | | Substrate sequence | ||
| − | | | + | | MAEPR''Q''EFEVM |
| + | GLGDR''K''DQGGY | ||
| + | GAPGK''Q''AAAQP | ||
| + | AGHVT''Q''ARMVS | ||
| + | APPGQ''K''GQANA | ||
| + | TRIPA''K''TPPAP''K''TPPSS | ||
| + | TREPK''K''VAVVR | ||
| + | AKSRL''Q''TAPVP | ||
| + | GGGKV''Q''IINKK | ||
| + | DLSNV''Q''SKCGS | ||
| + | FKDRV''Q''SKIGS | ||
| + | FRENA''K''A''K''TDHGA | ||
| + | MVDSP''Q''LATLA | ||
|- | |- | ||
| Structure | | Structure | ||
| − | | [http://www.rcsb.org/pdb/explore/explore.do?structureId= | + | | [http://www.rcsb.org/pdb/explore/explore.do?structureId=1I8H 1I8H] |
|- | |- | ||
| Surface accessibility | | Surface accessibility | ||
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| Notes | | Notes | ||
| − | | | + | | Bold indicates the predominant substrate sites for TG2. |
| + | |||
| + | Upon TG2 action the protein becomes less susceptible to μ-calpain mediated proteolysis. | ||
|- | |- | ||
| {{infobox header}} | | | {{infobox header}} | | ||
Revision as of 06:15, 24 July 2007
| Template:Infobox header| Tau protein | |
|---|---|
| Tau protein | |
| Substrate peptide name | Tau protein |
| Synonyms | - |
| Determination type | In situ |
| Source | Homo sapiens |
| Subcellular localization | Cytoskeleton |
| Swissprot ID | P10636 |
| Reactive glutamines | Q6, Q88, Q124, Q244, Q276, Q288, Q351, Q424 |
| Reactive lysines | K24, K163, K174, K180, K190, K225, K234, K240, K383, K385 |
| Substrate sequence | MAEPRQEFEVM
GLGDRKDQGGY GAPGKQAAAQP AGHVTQARMVS APPGQKGQANA TRIPAKTPPAPKTPPSS TREPKKVAVVR AKSRLQTAPVP GGGKVQIINKK DLSNVQSKCGS FKDRVQSKIGS FRENAKAKTDHGA MVDSPQLATLA |
| Structure | 1I8H |
| Surface accessibility | ASAView pdf |
| Disorder prediction | IUPred |
| Reference | PMID:9252372 |
| Notes | Bold indicates the predominant substrate sites for TG2.
Upon TG2 action the protein becomes less susceptible to μ-calpain mediated proteolysis. |
| Template:Infobox header | | |
