Difference between revisions of "RhoA"
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| Reactive glutamines | | Reactive glutamines | ||
− | | [[ | + | | [[TG2 reactive residues (RhoA)|Q52, Q63, Q136]] |
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| Reactive lysines | | Reactive lysines |
Revision as of 15:50, 17 August 2007
Template:Infobox header| RhoA | |
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RhoA | |
Substrate peptide name | RhoA |
Synonyms | - |
Determination type | In situ/In vitro |
Source | Homo sapiens |
Subcellular localization | Cytoskeleton |
Swissprot ID | P61586 |
Reactive glutamines | Q52, Q63, Q136 |
Reactive lysines | - |
Substrate sequence | EVDGKQVELAL
WDTAGQEDYDR LAKMKQEPVKP |
Structure | 1A2B |
Surface accessibility | ASAView pdf
ASAView txt |
Disorder prediction | IUPred |
Reference | PMID:9593707 |
Notes | Q63 is deamidated/transamidated by TG2
The transamidated protein has increased binding affinity to ROCK-2. The deamidated form (by cytotoxic dermonecrotizing factor or BTX) has decreased GTPase activity. |
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