Difference between revisions of "Alpha synuclein"
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{| class="toccolours" border="1" style="float: left; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;" | {| class="toccolours" border="1" style="float: left; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;" | ||
| − | ! | + | ! {infobox header}| '''{{PAGENAME}}''' |
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| − | | align="center" colspan="2" bgcolor="#ffffff" | [[Image: | + | | align="center" colspan="2" bgcolor="#ffffff" | [[Image:AlphaSynuclein.JPG|200px|{{PAGENAME}}]] |
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| Substrate peptide name | | Substrate peptide name | ||
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| Synonyms | | Synonyms | ||
| − | | - | + | | Non-A beta component of AD amyloid |
| + | Non-A4 component of amyloid precursor | ||
|- | |- | ||
| Determination type | | Determination type | ||
| − | | In situ | + | | In situ/In vitro |
|- | |- | ||
| Source | | Source | ||
| Line 18: | Line 18: | ||
|- | |- | ||
| Subcellular localization | | Subcellular localization | ||
| − | | | + | | Cytosol |
|- | |- | ||
| Swissprot ID | | Swissprot ID | ||
| − | | [http://au.expasy.org/uniprot/ | + | | [http://au.expasy.org/uniprot/P37840 P37840] |
|- | |- | ||
| Reactive glutamines | | Reactive glutamines | ||
| − | | [[ | + | | [[TG2 reactive residues (Synuclein)|Q79, Q99]] |
|- | |- | ||
| Reactive lysines | | Reactive lysines | ||
| − | | | + | | [[TG2 reactive residues (Synuclein)|K80]] |
|- | |- | ||
| Substrate sequence | | Substrate sequence | ||
| − | | | + | | VTAVA''QK''TVEGA |
| + | |||
| + | FVKKD''Q''LGKNE | ||
| + | |||
|- | |- | ||
| Structure | | Structure | ||
| − | | [http://www.rcsb.org/pdb/explore/explore.do?structureId= | + | | [http://www.rcsb.org/pdb/explore/explore.do?structureId=1XQ8 1XQ8 ] |
|- | |- | ||
| Surface accessibility | | Surface accessibility | ||
| − | | [http://gibk21.bse.kyutech.ac.jp/asaview/ | + | | [http://gibk21.bse.kyutech.ac.jp/netasa/asaview/tmp/120866ext.pdf ASAView] pdf |
| + | [http://gibk21.bse.kyutech.ac.jp/netasa/asaview/tmp/120866ext.asa.asa.out ASAView] txt | ||
|- | |- | ||
| Disorder prediction | | Disorder prediction | ||
| Line 42: | Line 46: | ||
|- | |- | ||
| Reference | | Reference | ||
| − | | [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids= | + | | [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=12576551&dopt=Abstract PMID:12576551] |
|- | |- | ||
| Notes | | Notes | ||
| | | | ||
|- | |- | ||
| − | | | + | | {infobox header} | |
|- | |- | ||
|} | |} | ||
[[Category:Tissue transglutaminase|*]] | [[Category:Tissue transglutaminase|*]] | ||
Latest revision as of 11:21, 10 March 2015
| Alpha synuclein | |
|---|---|
| |
| Substrate peptide name | Alpha synuclein |
| Synonyms | Non-A beta component of AD amyloid
Non-A4 component of amyloid precursor |
| Determination type | In situ/In vitro |
| Source | Homo sapiens |
| Subcellular localization | Cytosol |
| Swissprot ID | P37840 |
| Reactive glutamines | Q79, Q99 |
| Reactive lysines | K80 |
| Substrate sequence | VTAVAQKTVEGA
FVKKDQLGKNE |
| Structure | 1XQ8 |
| Surface accessibility | ASAView pdf
ASAView txt |
| Disorder prediction | IUPred |
| Reference | PMID:12576551 |
| Notes | |
