Difference between revisions of "Retinoblastoma protein (kinase)"
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| Substrate peptide name | | Substrate peptide name | ||
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| Determination type | | Determination type | ||
| − | | | + | | In vitro |
|- | |- | ||
| Source | | Source | ||
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| Phosphorilated residues | | Phosphorilated residues | ||
| − | |S780 | + | |[[Phosphorilated residues (pRB)|S780]] |
|- | |- | ||
| Substrate sequence | | Substrate sequence | ||
| − | | | + | | RPPTL''S''PIPHI |
|- | |- | ||
| Structure | | Structure | ||
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| Notes | | Notes | ||
| − | | Phosphorylation of Rb protein by TG2 is associated with destabilization of the pRB/E2F1 complex. The cross-linked Rb is only lightly phosphorilated. | + | | Phosphorylation of Rb protein by TG2 is associated with destabilization of the pRB/E2F1 complex. |
| + | The cross-linked Rb is only lightly phosphorilated. | ||
|- | |- | ||
| {{infobox header}} | | | {{infobox header}} | | ||
Latest revision as of 08:47, 4 September 2007
| Template:Infobox header| Retinoblastoma protein (kinase) | |
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| Substrate peptide name | Retinoblastoma protein (kinase) |
| Synonyms | pRB |
| Determination type | In vitro |
| Source | Homo sapiens |
| Subcellular localization | Nucleus |
| Swissprot ID | Q92722 |
| Phosphorilated residues | S780 |
| Substrate sequence | RPPTLSPIPHI |
| Structure | 1N4M |
| Surface accessibility | |
| Disorder prediction | IUPred |
| Reference | PMID:17478427 |
| Notes | Phosphorylation of Rb protein by TG2 is associated with destabilization of the pRB/E2F1 complex.
The cross-linked Rb is only lightly phosphorilated. |
| Template:Infobox header | | |
