Difference between revisions of "CD38"

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| Substrate peptide name
 
| Substrate peptide name
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|-
 
|-
 
| Synonyms
 
| Synonyms
| -
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| ADP-ribosyl cyclase 1
 
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|-
 
| Determination type
 
| Determination type
| In situ
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| In situ/In vitro
 
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|-
 
| Source
 
| Source
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|-
 
|-
 
| Subcellular localization
 
| Subcellular localization
| Cytoskeleton
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| Plasma membrane
 
|-
 
|-
 
| Swissprot ID
 
| Swissprot ID
| [http://au.expasy.org/uniprot/P08865 P08865]
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| [http://au.expasy.org/uniprot/P28907 P28907 ]
 
|-
 
|-
 
| Reactive glutamines
 
| Reactive glutamines
| [[Q41 (Actin)|Q41]]
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| Not determined yet
 
|-
 
|-
 
| Reactive lysines
 
| Reactive lysines
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|-
 
|-
 
| Substrate sequence
 
| Substrate sequence
| GRPRHQGVMVG
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|  
 
|-
 
|-
 
| Structure
 
| Structure
| [http://www.rcsb.org/pdb/explore/explore.do?structureId=2BTF 2BTF]
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| [http://www.rcsb.org/pdb/explore/explore.do?structureId=1LBE 1LBE]
 
|-
 
|-
 
| Surface accessibility
 
| Surface accessibility
| [http://gibk21.bse.kyutech.ac.jp/asaview/all/2btfA.pdf ASAView] pdf
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|  
 
|-
 
|-
 
| Disorder prediction
 
| Disorder prediction
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|-
 
|-
 
| Reference
 
| Reference
| [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=9252372&dopt=Abstract PMID:9252372]
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| [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=8663150&dopt=Abstract PMID:8663150]
 
|-
 
|-
 
| Notes
 
| Notes
|  
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| TG2 catalyze the dimerization and multimerization of CD38 protein
 +
 
 +
Upon crosslinking by TG2 the cyclase activity increases and the hydrolase activity decreases
 +
 
 
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[[Category:Tissue transglutaminase|*]]
 
[[Category:Tissue transglutaminase|*]]

Latest revision as of 11:30, 10 March 2015

CD38
Substrate peptide name CD38
Synonyms ADP-ribosyl cyclase 1
Determination type In situ/In vitro
Source Homo sapiens
Subcellular localization Plasma membrane
Swissprot ID P28907
Reactive glutamines Not determined yet
Reactive lysines Not determined yet
Substrate sequence
Structure 1LBE
Surface accessibility
Disorder prediction IUPred
Reference PMID:8663150
Notes TG2 catalyze the dimerization and multimerization of CD38 protein

Upon crosslinking by TG2 the cyclase activity increases and the hydrolase activity decreases