Difference between revisions of "Serotonin"
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| Substrate peptide name | | Substrate peptide name | ||
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| Source | | Source | ||
| Bos taurus | | Bos taurus | ||
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+ | Rattus norvegicus | ||
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| Subcellular localization | | Subcellular localization | ||
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| Reference | | Reference | ||
| [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=17142836&dopt=Abstract PMID:17142836] | | [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=17142836&dopt=Abstract PMID:17142836] | ||
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+ | [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=19479059&dopt=Abstract PMID:19479059] | ||
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| Notes | | Notes | ||
| 5-HT covalently modifies proteins integral to contractility and the cytoskeleton (ex. alpha-actin). Serotonilation of proteins suggest new mechanisms of action for 5-HT in vascular smooth muscle and consideration for intracellular effects of primary amines. | | 5-HT covalently modifies proteins integral to contractility and the cytoskeleton (ex. alpha-actin). Serotonilation of proteins suggest new mechanisms of action for 5-HT in vascular smooth muscle and consideration for intracellular effects of primary amines. | ||
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− | | | + | | {infobox header} | |
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[[Category:Tissue transglutaminase|*]] | [[Category:Tissue transglutaminase|*]] |
Latest revision as of 11:56, 10 March 2015
Serotonin | |
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Substrate peptide name | Serotonin |
Synonyms | 5-HT, 5-hydroxi-triptamine |
Determination type | In vivo |
Source | Bos taurus
Rattus norvegicus |
Subcellular localization | Extracellular; secreted signal molecule |
Swissprot ID | - |
Reactive glutamines | Not determined yet |
Reactive lysines | Not determined yet |
Substrate sequence | |
Structure | |
Surface accessibility | |
Disorder prediction | |
Reference | PMID:17142836 |
Notes | 5-HT covalently modifies proteins integral to contractility and the cytoskeleton (ex. alpha-actin). Serotonilation of proteins suggest new mechanisms of action for 5-HT in vascular smooth muscle and consideration for intracellular effects of primary amines. |