Difference between revisions of "Phospholipase A2 (TG2)"
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| − | ! | + | ! {infobox header}| '''{{PAGENAME}}''' |
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| − | | align="center" colspan="2" bgcolor="#ffffff" | [[Image: | + | | align="center" colspan="2" bgcolor="#ffffff" | [[Image:PLA2.JPG|200px|{{PAGENAME}}]] |
|- | |- | ||
| Substrate peptide name | | Substrate peptide name | ||
| − | | | + | | Phospholipase A2 |
|- | |- | ||
| Synonyms | | Synonyms | ||
| − | | | + | | PLA2 |
|- | |- | ||
| Determination type | | Determination type | ||
| − | | In | + | | In vitro |
|- | |- | ||
| Source | | Source | ||
| − | | | + | | Sus scrofa, Naja naja, Apis sp. |
|- | |- | ||
| Subcellular localization | | Subcellular localization | ||
| − | | | + | | Cytosol |
| + | Venom | ||
|- | |- | ||
| Swissprot ID | | Swissprot ID | ||
| − | | [http://au.expasy.org/uniprot/ | + | | [http://au.expasy.org/uniprot/P00592 P00592 ] |
|- | |- | ||
| Reactive glutamines | | Reactive glutamines | ||
| − | | [[ | + | | [[TG2 reactive residues (Phospholipase A2)|Q4]] |
|- | |- | ||
| Reactive lysines | | Reactive lysines | ||
| − | | | + | |[[TG2 reactive residues (Phospholipase A2)|K10]] |
|- | |- | ||
| Substrate sequence | | Substrate sequence | ||
| − | | | + | | ALW''Q''FRSMI''K''CAIPG |
|- | |- | ||
| Structure | | Structure | ||
| − | | [http://www.rcsb.org/pdb/explore/explore.do?structureId= | + | | [http://www.rcsb.org/pdb/explore/explore.do?structureId=1HN4 1HN4] |
|- | |- | ||
| Surface accessibility | | Surface accessibility | ||
| − | | [http://gibk21.bse.kyutech.ac.jp/asaview/all/ | + | | [http://gibk21.bse.kyutech.ac.jp/asaview/all/1hn4A.pdf ASAView] pdf |
| + | [http://gibk21.bse.kyutech.ac.jp/asaview/all/1hn4A.txt ASAView] txt | ||
|- | |- | ||
| Disorder prediction | | Disorder prediction | ||
| Line 42: | Line 43: | ||
|- | |- | ||
| Reference | | Reference | ||
| − | | [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids= | + | | [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=1976627&dopt=Abstract PMID:1976627] |
|- | |- | ||
| Notes | | Notes | ||
| − | | | + | | Transglutaminase probably catalyze the formation of intramolecular isopeptide bonds |
| + | |||
| + | and this enhances the noncovalent interaction of monomers. | ||
| + | |||
| + | The crosslinking by transglutaminase enhances it's activity. | ||
| + | |- | ||
| + | |Video | ||
| + | |{{#ev:dailymotion|4BZwJSIDhgCWVkY35|300}} | ||
|- | |- | ||
| − | | | + | | {infobox header} | |
|- | |- | ||
|} | |} | ||
[[Category:Tissue transglutaminase|*]] | [[Category:Tissue transglutaminase|*]] | ||
Latest revision as of 11:51, 10 March 2015
| Phospholipase A2 (TG2) | |
|---|---|
| |
| Substrate peptide name | Phospholipase A2 |
| Synonyms | PLA2 |
| Determination type | In vitro |
| Source | Sus scrofa, Naja naja, Apis sp. |
| Subcellular localization | Cytosol
Venom |
| Swissprot ID | P00592 |
| Reactive glutamines | Q4 |
| Reactive lysines | K10 |
| Substrate sequence | ALWQFRSMIKCAIPG |
| Structure | 1HN4 |
| Surface accessibility | ASAView pdf
ASAView txt |
| Disorder prediction | IUPred |
| Reference | PMID:1976627 |
| Notes | Transglutaminase probably catalyze the formation of intramolecular isopeptide bonds
and this enhances the noncovalent interaction of monomers. The crosslinking by transglutaminase enhances it's activity. |
| Video | 4BZwJSIDhgCWVkY35|300}} |
