Difference between revisions of "S100A11 (TG2)"

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| Substrate peptide name
 
| Substrate peptide name
| {{PAGENAME}}
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| S100A11 
 
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|-
 
| Synonyms
 
| Synonyms
| S100 calcium-binding protein A10
+
|   S100 calcium-binding protein A11
Calpactin-1 light chain
+
Calgizzarin
 
|-
 
|-
 
| Determination type
 
| Determination type
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|-
 
| Swissprot ID
 
| Swissprot ID
| [http://au.expasy.org/uniprot/P60903 P60903 ]
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| [http://au.expasy.org/uniprot/P31949 P31949 ]
 
|-
 
|-
 
| Reactive glutamines
 
| Reactive glutamines
| [[K3, Q102 (S100A11)|Q102]]
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| [[TG2 reactive residues (S100A11)|Q102]]
 
|-
 
|-
 
| Reactive lysines
 
| Reactive lysines
| [[K3, Q102 (S100A11)|K3]]
+
| K3
 
|-
 
|-
 
| Substrate sequence
 
| Substrate sequence
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|-
 
|-
 
| Surface accessibility
 
| Surface accessibility
| [http://gibk21.bse.kyutech.ac.jp/asaview/all/2btfA.pdf ASAView] pdf
+
| [http://gibk21.bse.kyutech.ac.jp/asaview/all/1qlsA.pdf ASAView] pdf
 +
[http://gibk21.bse.kyutech.ac.jp/asaview/all/1qlsA.txt ASAView] txt
 
|-
 
|-
 
| Disorder prediction
 
| Disorder prediction
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|-
 
|-
 
| Notes
 
| Notes
| TG2 catalyze the formation of dimers and multimers
+
|Transamidation by TG2 transforms S100A11 into a covalently bonded homodimer
 +
 
 +
that acquires the capacity to signal through the p38 MAPK pathway, accelerate
 +
 
 +
chondrocyte hypertrophy and matrix catabolism.
 +
|-
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|Video
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|{{#ev:dailymotion|1qxapT72gvd7lkY0F|300}}
 
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[[Category:Tissue transglutaminase|*]]
 
[[Category:Tissue transglutaminase|*]]

Latest revision as of 11:55, 10 March 2015

S100A11 (TG2)
S100A11 (TG2)
Substrate peptide name S100A11
Synonyms S100 calcium-binding protein A11

Calgizzarin

Determination type In situ/In vitro
Source Homo sapiens
Subcellular localization Cytosol

Keratinocyte cornified envelope

Swissprot ID P31949
Reactive glutamines Q102
Reactive lysines K3
Substrate sequence KAVPSQKRT

MASKISSPT

Structure 1QLS
Surface accessibility ASAView pdf

ASAView txt

Disorder prediction IUPred
Reference PMID:9446578
Notes Transamidation by TG2 transforms S100A11 into a covalently bonded homodimer

that acquires the capacity to signal through the p38 MAPK pathway, accelerate

chondrocyte hypertrophy and matrix catabolism.

Video 1qxapT72gvd7lkY0F|300}}