Difference between revisions of "Desmoplakin (TG1)"
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{| class="toccolours" border="1" style="float: left; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;" | {| class="toccolours" border="1" style="float: left; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;" | ||
| − | ! | + | ! {infobox header}| '''{{PAGENAME}}''' |
|- | |- | ||
| − | | align="center" colspan="2" bgcolor="#ffffff" | [[Image: | + | | align="center" colspan="2" bgcolor="#ffffff" | [[Image:Desmoplakin.JPG|200px|{{PAGENAME}}]] |
|- | |- | ||
| Substrate peptide name | | Substrate peptide name | ||
| − | | | + | | Desmoplakin |
|- | |- | ||
| Synonyms | | Synonyms | ||
| Line 23: | Line 23: | ||
| [http://au.expasy.org/uniprot/P15924 P15924 ] | | [http://au.expasy.org/uniprot/P15924 P15924 ] | ||
|- | |- | ||
| − | | Reactive glutamines | + | | Reactive glutamines |
| − | | [[ | + | | [[TG2 reactive residues (Desmoplakin)|Q1646]] |
|- | |- | ||
| Reactive lysines | | Reactive lysines | ||
| − | | [[ | + | | [[TG2 reactive residues (Desmoplakin)|K1659, K1661, K1667]] |
|- | |- | ||
| Substrate sequence | | Substrate sequence | ||
| AAQRL''Q''DTSSY | | AAQRL''Q''DTSSY | ||
| + | ILTCP''K''T''K''LKISY''K''DAIN | ||
|- | |- | ||
| Structure | | Structure | ||
| − | | | + | | [http://www.rcsb.org/pdb/explore/explore.do?structureId=1LM5 1LM5] |
|- | |- | ||
| Surface accessibility | | Surface accessibility | ||
| − | | | + | | [http://gibk21.bse.kyutech.ac.jp/asaview/all/1lm5.pdf ASAView] pdf |
| + | [http://gibk21.bse.kyutech.ac.jp/asaview/all/1lm5.txt ASAView] txt | ||
|- | |- | ||
| Disorder prediction | | Disorder prediction | ||
| Line 42: | Line 44: | ||
|- | |- | ||
| Reference | | Reference | ||
| − | | [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids= | + | | [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=1689290&dopt=Abstract PMID:1689290] |
| + | [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=7543090&dopt=Abstract PMID:7543090] | ||
|- | |- | ||
| Notes | | Notes | ||
| − | | According to literature references, the reactive Q residue is Q1646 but in primary sequence and crystal structure this residue is situated in position 2765 | + | | According to literature references, the reactive Q residue is Q1646 but |
| + | in primary sequence and crystal structure this residue is situated in position 2765 | ||
|- | |- | ||
| − | | {{infobox header | + | |Video |
| + | |{{#ev:dailymotion|51YFirXHGQTtVkY3x|300}} | ||
| + | |- | ||
| + | | {infobox header} | | ||
|- | |- | ||
|} | |} | ||
[[Category:Keratinocyte transglutaminase|*]] | [[Category:Keratinocyte transglutaminase|*]] | ||
Latest revision as of 11:16, 10 March 2015
| Desmoplakin (TG1) | |
|---|---|
| |
| Substrate peptide name | Desmoplakin |
| Synonyms | - |
| Determination type | In situ |
| Source | Homo sapiens |
| Subcellular localization | Cornified envelope
Cytoskeleton |
| Swissprot ID | P15924 |
| Reactive glutamines | Q1646 |
| Reactive lysines | K1659, K1661, K1667 |
| Substrate sequence | AAQRLQDTSSY
ILTCPKTKLKISYKDAIN |
| Structure | 1LM5 |
| Surface accessibility | ASAView pdf
ASAView txt |
| Disorder prediction | IUPred |
| Reference | PMID:1689290 |
| Notes | According to literature references, the reactive Q residue is Q1646 but
in primary sequence and crystal structure this residue is situated in position 2765 |
| Video | 51YFirXHGQTtVkY3x|300}} |
