Difference between revisions of "Insulin"

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|-
 
|-
 
| Determination type
 
| Determination type
| In situ
+
| In vitro
 
|-
 
|-
 
| Source
 
| Source
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|-
 
|-
 
| Subcellular localization
 
| Subcellular localization
| Cytoskeleton
+
| Extracellular; plasma
 
|-
 
|-
 
| Swissprot ID
 
| Swissprot ID
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|-
 
|-
 
| Reactive glutamines
 
| Reactive glutamines
| [[Q41 (Actin)|Q41]]
+
| [[Q5, Q15 (Insulin)|chain A - Q5, Q15]]
 +
[[Q4 (Insulin)|chain B - Q4]]
 
|-
 
|-
 
| Reactive lysines
 
| Reactive lysines
| Not determined yet
+
| -
 
|-
 
|-
 
| Substrate sequence
 
| Substrate sequence
| GRPRHQGVMVG
+
| chain A - GIVE''Q''C*C*ASVC*SLY''Q''LENYC*N
 +
chain B - FVN''Q''HLC*GS
 +
 
 
|-
 
|-
 
| Structure
 
| Structure
| [http://www.rcsb.org/pdb/explore/explore.do?structureId=2BTF 2BTF]
+
| [http://www.rcsb.org/pdb/explore/explore.do?structureId=1BEN 1BEN]
 
|-
 
|-
 
| Surface accessibility
 
| Surface accessibility
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|-
 
|-
 
| Reference
 
| Reference
| [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=9252372&dopt=Abstract PMID:9252372]
+
| [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=14342319&dopt=Abstract PMID:14342319]
 
|-
 
|-
 
| Notes
 
| Notes
|  
+
| * the Cys residues are oxidized
 
|-
 
|-
 
| {{infobox header}} |  
 
| {{infobox header}} |  

Revision as of 12:41, 23 July 2007

Template:Infobox header| Insulin
Insulin
Substrate peptide name Insulin
Synonyms -
Determination type In vitro
Source Homo sapiens
Subcellular localization Extracellular; plasma
Swissprot ID P08865
Reactive glutamines chain A - Q5, Q15

chain B - Q4

Reactive lysines -
Substrate sequence chain A - GIVEQC*C*ASVC*SLYQLENYC*N

chain B - FVNQHLC*GS

Structure 1BEN
Surface accessibility ASAView pdf
Disorder prediction IUPred
Reference PMID:14342319
Notes * the Cys residues are oxidized
Template:Infobox header |