Difference between revisions of "RhoA"

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| Swissprot ID
 
| Swissprot ID
| [http://au.expasy.org/uniprot/P06749 P06749 ]
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| [http://au.expasy.org/uniprot/P61586 P61586 ]
 
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| Reactive glutamines
 
| Reactive glutamines

Revision as of 05:16, 24 July 2007

Template:Infobox header| RhoA
RhoA
Substrate peptide name RhoA
Synonyms -
Determination type In situ/In vitro
Source Homo sapiens
Subcellular localization Cytoskeleton
Swissprot ID P61586
Reactive glutamines Q52, Q63, Q136
Reactive lysines -
Substrate sequence EVDGKQVELAL

WDTAGQEDYDR

LAKMKQEPVKP

Structure 1A2B
Surface accessibility ASAView pdf
Disorder prediction IUPred
Reference PMID:9593707
Notes Q63 is deamidated/transamidated by TG2

The transamidated protein has increased binding affinity to ROCK-2. The deamidated form (by cytotoxic dermonecrotizing factor or BTX) has decreased GTPase activity.

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