Difference between revisions of "Tau protein"
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| Synonyms | | Synonyms | ||
| − | | - | + | | Microtubule-associated protein tau |
| + | Neurofibrillary tangle protein | ||
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| Determination type | | Determination type | ||
Revision as of 06:18, 24 July 2007
| Template:Infobox header| Tau protein | |
|---|---|
| Tau protein | |
| Substrate peptide name | Tau protein |
| Synonyms | Microtubule-associated protein tau
Neurofibrillary tangle protein |
| Determination type | In situ |
| Source | Homo sapiens |
| Subcellular localization | Cytoskeleton |
| Swissprot ID | P10636 |
| Reactive glutamines | Q6, Q88, Q124, Q244, Q276, Q288, Q351, Q424 |
| Reactive lysines | K24, K163, K174, K180, K190, K225, K234, K240, K383, K385 |
| Substrate sequence | MAEPRQEFEVM, GLGDRKDQGGY,
GAPGKQAAAQP, AGHVTQARMVS, APPGQKGQANA, TRIPAKTPPAPKTPPSS, TREPKKVAVVR, AKSRLQTAPVP, GGGKVQIINKK, DLSNVQSKCGS, FKDRVQSKIGS, FRENAKAKTDHGA, MVDSPQLATLA |
| Structure | 1I8H |
| Surface accessibility | ASAView pdf |
| Disorder prediction | IUPred |
| Reference | PMID:9832162 |
| Notes | Bold indicates the predominant substrate sites for TG2.
Upon TG2 action the protein becomes less susceptible to μ-calpain mediated proteolysis. |
| Template:Infobox header | | |
