Serotonin
Serotonin | |
---|---|
Substrate peptide name | Serotonin |
Synonyms | 5-HT, 5-hydroxi-triptamine |
Determination type | In vivo |
Source | Bos taurus
Rattus norvegicus |
Subcellular localization | Extracellular; secreted signal molecule |
Swissprot ID | - |
Reactive glutamines | Not determined yet |
Reactive lysines | Not determined yet |
Substrate sequence | |
Structure | |
Surface accessibility | |
Disorder prediction | |
Reference | PMID:17142836 |
Notes | 5-HT covalently modifies proteins integral to contractility and the cytoskeleton (ex. alpha-actin). Serotonilation of proteins suggest new mechanisms of action for 5-HT in vascular smooth muscle and consideration for intracellular effects of primary amines. |