Tau protein

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Template:Infobox header| Tau protein
Tau protein
Substrate peptide name Tau protein
Synonyms -
Determination type In situ
Source Homo sapiens
Subcellular localization Cytoskeleton
Swissprot ID P10636
Reactive glutamines Q6, Q88, Q124, Q244, Q276, Q288, Q351, Q424
Reactive lysines K24, K163, K174, K180, K190, K225, K234, K240, K383, K385
Substrate sequence MAEPRQEFEVM

GLGDRKDQGGY GAPGKQAAAQP AGHVTQARMVS APPGQKGQANA TRIPAKTPPAPKTPPSS TREPKKVAVVR AKSRLQTAPVP GGGKVQIINKK DLSNVQSKCGS FKDRVQSKIGS FRENAKAKTDHGA MVDSPQLATLA

Structure 1I8H
Surface accessibility ASAView pdf
Disorder prediction IUPred
Reference PMID:9252372
Notes Bold indicates the predominant substrate sites for TG2.

Upon TG2 action the protein becomes less susceptible to μ-calpain mediated proteolysis.

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