Template:Infobox header| Serotonin
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Substrate peptide name
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Serotonin
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Synonyms
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5-HT, 5-hydroxi-triptamine
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Determination type
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In vivo
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Source
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Bos taurus
Rattus norvegicus
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Subcellular localization
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Extracellular; secreted signal molecule
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Swissprot ID
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-
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Reactive glutamines
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Not determined yet
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Reactive lysines
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Not determined yet
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Substrate sequence
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Structure
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Surface accessibility
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Disorder prediction
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Reference
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PMID:17142836
PMID:19479059
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Notes
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5-HT covalently modifies proteins integral to contractility and the cytoskeleton (ex. alpha-actin). Serotonilation of proteins suggest new mechanisms of action for 5-HT in vascular smooth muscle and consideration for intracellular effects of primary amines.
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