| Template:Infobox header| PTEN
|
| Substrate peptide name
|
PTEN - Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase
|
| Synonyms
|
-
|
| Determination type
|
In situ
|
| Source
|
Homo sapiens
|
| Subcellular localization
|
Cytosol
|
| Swissprot ID
|
P60484
|
| Interacting residues
|
Not determined yet
|
| Interacting sequence
|
Not determined yet
|
| TG2 Swissprot ID
|
P21980
|
| Interacting residues of TG2
|
Not determined yet
|
| Interacting sequence of TG2
|
Not determined yet
|
| Structure
|
1D5R
|
| Surface accessibility
|
|
| Disorder prediction
|
IUPred
|
| Reference
|
PMID:18381937
|
| Notes
|
TG2 promotes the hypophosphorilation and degradation of PTEN by ubiquitin-proteasomal pathway and results in constitutive activation of focal adhesion kinase/AKT cell survival signaling.
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| Template:Infobox header |
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