RhoA

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RhoA
RhoA
Substrate peptide name RhoA
Synonyms -
Determination type In situ/In vitro
Source Homo sapiens
Subcellular localization Cytoskeleton
Swissprot ID P61586
Reactive glutamines Q52, Q63, Q136
Reactive lysines -
Substrate sequence EVDGKQVELAL

WDTAGQEDYDR

LAKMKQEPVKP

Structure 1A2B
Surface accessibility ASAView pdf

ASAView txt

Disorder prediction IUPred
Reference PMID:9593707
Notes Q63 is deamidated/transamidated by TG2

The transamidated protein has increased binding affinity to ROCK-2.

The deamidated form (by cytotoxic dermonecrotizing factor or BTX) has decreased GTPase activity.

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