PTEN
| PTEN | |
|---|---|
| Substrate peptide name | PTEN - Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and
dual-specificity protein phosphatase |
| Synonyms | - |
| Determination type | In situ |
| Source | Homo sapiens |
| Subcellular localization | Cytosol |
| Swissprot ID | P60484 |
| Interacting residues | Not determined yet |
| Interacting sequence | Not determined yet |
| TG2 Swissprot ID | P21980 |
| Interacting residues of TG2 | Not determined yet |
| Interacting sequence of TG2 | Not determined yet |
| Structure | 1D5R |
| Surface accessibility | |
| Disorder prediction | IUPred |
| Reference | PMID:18381937 |
| Notes | TG2 promotes the hypophosphorilation and degradation of PTEN by ubiquitin-proteasomal
pathway and results in constitutive activation of focal adhesion kinase/AKT cell survival signaling. |
