Collagen (TG2)

From MyMediaWiki
Jump to: navigation, search
Collagen (TG2)
Substrate peptide name Collagen
Synonyms -
Determination type In vitro
Source Homo sapiens
Subcellular localization Cytosol/Extracellular
Swissprot ID P02461

P020908 Q02388 P12107

Reactive glutamines III.-Q14

proVII.-Q2796, Q2800, Q2805, Q2807*

Reactive lysines Not determined yet
Substrate sequence III.-CSHLGQSYADR

VII.-RGFVRQEMSQHCACQGQFIASG*

Structure No available crystal structure
Surface accessibility
Disorder prediction IUPred
Reference PMID:2879837

PMID:8787681 PMID:7577969

Notes * These residues are potential TG2 glutamine donor substrates situated on NC-2 domain of procollagen VII.

The crosslink catalyzed by transglutaminases are important for the protein's physiological functions