Exendin 4

From MyMediaWiki
Jump to: navigation, search
Exendin 4
Substrate peptide name Exendin 4
Synonyms Exenatide
Determination type In vitro
Source Heloderma suspectum
Subcellular localization Excreted
Swissprot ID P26349
Reactive glutamines -
Reactive lysines K12, K27
Substrate sequence TSDLSKQMEEE

FIEWLKNGGPS

Structure 1JRJ
Surface accessibility
Disorder prediction IUPred
Reference PMID:18761350
Notes It is a GIP-1 incretin mimetic having a role in the regulation of blood glucose level.

It is used in the medication of type II diabetes as Byetta (Amylin, Lilly).