Hypoxia inducible factor 1
Hypoxia inducible factor 1 | |
---|---|
Substrate peptide name | Hypoxia-inducible factor 1-beta |
Synonyms | Aryl hydrocarbon receptor nuclear translocator
Dioxin receptor, nuclear translocator |
Determination type | in situ/in vitro |
Source | Homo sapiens |
Subcellular localization | Cytosol/Nucleus |
Swissprot ID | P27540 |
Interacting residues | Not determined yet |
Interacting sequence | Not determined yet |
TG2 Swissprot ID | P21980 |
Interacting residues of TG2 | Not determined yet |
Interacting sequence of TG2 | Not determined yet |
Structure | 4EQ1 |
Surface accessibility | - |
Disorder prediction | IUPred |
Reference | PMID:18375543 |
Notes | TG2 inhibited a HIF-dependent transcription under hypoxic conditions without affecting nuclear protein levels
for HIF1{alpha} or HIF1{beta}, their ability to form the HIF1 heterodimeric transcription factor, or HIF1 binding to its DNA response element. |