Midkine

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Midkine
Midkine N-terminal part}Midkine C-terminal part
Substrate peptide name Midkine
Synonyms Neurite outgrowth-promoting protein

Midgestation and kidney protein

Amphiregulin-associated protein

Determination type In vitro
Source Homo sapiens
Subcellular localization Extracellular, plasma
Swissprot ID P21741
Reactive glutamines Q42, Q44, Q95
Reactive lysines K63
Substrate sequence GTCGAQTQRIRCR

NAQCQETIRV

FGADCKYKFEN

Structure 1MKN

1MKC

Surface accessibility ASAView pdf

ASAView txt

ASAView pdf

ASAView txt

Disorder prediction IUPred
Reference PMID:9083079

PMID:9384573

Notes It seems that Q42 and Q44 serve alternatively as glutamine donor substrates

It has enhanced activity upon crosslinking by TG2.

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