Difference between revisions of "Amyloid beta A4 peptide"
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{| class="toccolours" border="1" style="float: left; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;" | {| class="toccolours" border="1" style="float: left; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;" | ||
| − | ! | + | ! {infobox header}| '''{{PAGENAME}}''' |
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| − | | align="center" colspan="2" bgcolor="#ffffff" | [[Image: | + | | align="center" colspan="2" bgcolor="#ffffff" | [[Image:Beta_amyloid.JPG|200px|{{PAGENAME}}]] |
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| Substrate peptide name | | Substrate peptide name | ||
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|- | |- | ||
| Synonyms | | Synonyms | ||
| − | | | + | | Alzheimer disease amyloid protein |
|- | |- | ||
| Determination type | | Determination type | ||
| − | | In | + | | In vitro |
|- | |- | ||
| Source | | Source | ||
| Line 18: | Line 17: | ||
|- | |- | ||
| Subcellular localization | | Subcellular localization | ||
| − | | | + | | Extracellular; cerebrospinal fluid |
| + | Alzheimer's disease neuritic plaques | ||
| + | |||
|- | |- | ||
| Swissprot ID | | Swissprot ID | ||
| − | | [http://au.expasy.org/uniprot/ | + | | [http://au.expasy.org/uniprot/P05067 P05067] |
|- | |- | ||
| Reactive glutamines | | Reactive glutamines | ||
| − | | [[ | + | | [[TG2 reactive residues (APP)|Q15]] |
|- | |- | ||
| − | | Reactive lysines | + | | Reactive lysines |
| − | | | + | | [[TG2 reactive residues (APP)|K16, K28]] |
|- | |- | ||
| Substrate sequence | | Substrate sequence | ||
| − | | | + | | YEVHH''QK''LVFFA |
| + | |||
| + | DVGSN''K''GAIIG | ||
| + | |||
|- | |- | ||
| Structure | | Structure | ||
| − | | [http://www.rcsb.org/pdb/explore/explore.do?structureId= | + | | [http://www.rcsb.org/pdb/explore/explore.do?structureId=1AML 1AML ] |
|- | |- | ||
| Surface accessibility | | Surface accessibility | ||
| − | | [http://gibk21.bse.kyutech.ac.jp/asaview/all/ | + | | [http://gibk21.bse.kyutech.ac.jp/asaview/all/1aml.pdf ASAView] pdf |
| + | [http://gibk21.bse.kyutech.ac.jp/asaview/all/1aml.txt ASAView] txt | ||
|- | |- | ||
| Disorder prediction | | Disorder prediction | ||
| Line 42: | Line 47: | ||
|- | |- | ||
| Reference | | Reference | ||
| − | | [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids= | + | | [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=7905838&dopt=Abstract PMID:7905838] |
|- | |- | ||
| Notes | | Notes | ||
| | | | ||
|- | |- | ||
| − | | {{infobox header | + | | Video |
| + | |{{#ev:dailymotion|7qzKHArw798dckRrh|300}} | ||
| + | |- | ||
| + | | {infobox header} | | ||
|- | |- | ||
|} | |} | ||
[[Category:Tissue transglutaminase|*]] | [[Category:Tissue transglutaminase|*]] | ||
Latest revision as of 11:23, 10 March 2015
| Amyloid beta A4 peptide | |
|---|---|
| |
| Substrate peptide name | Amyloid beta A4 peptide |
| Synonyms | Alzheimer disease amyloid protein |
| Determination type | In vitro |
| Source | Homo sapiens |
| Subcellular localization | Extracellular; cerebrospinal fluid
Alzheimer's disease neuritic plaques |
| Swissprot ID | P05067 |
| Reactive glutamines | Q15 |
| Reactive lysines | K16, K28 |
| Substrate sequence | YEVHHQKLVFFA
DVGSNKGAIIG |
| Structure | 1AML |
| Surface accessibility | ASAView pdf
ASAView txt |
| Disorder prediction | IUPred |
| Reference | PMID:7905838 |
| Notes | |
| Video | 7qzKHArw798dckRrh|300}} |
