Difference between revisions of "Exendin 4"
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| Substrate peptide name | | Substrate peptide name | ||
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| Source | | Source | ||
| − | | | + | | Heloderma suspectum |
|- | |- | ||
| Subcellular localization | | Subcellular localization | ||
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| Swissprot ID | | Swissprot ID | ||
| − | | [http://au.expasy.org/uniprot/ | + | | [http://au.expasy.org/uniprot/P26349 P26349] |
|- | |- | ||
| Reactive glutamines | | Reactive glutamines | ||
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| Substrate sequence | | Substrate sequence | ||
| − | | | + | | TSDLS''K''QMEEE |
| + | FIEWL''K''NGGPS | ||
|- | |- | ||
| Structure | | Structure | ||
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|- | |- | ||
| Notes | | Notes | ||
| − | | | + | | It is a GIP-1 incretin mimetic having a role in the regulation of blood glucose level. |
| + | It is used in the medication of type II diabetes as Byetta (Amylin, Lilly). | ||
|- | |- | ||
| − | | | + | | {infobox header} | |
|- | |- | ||
|} | |} | ||
[[Category:Tissue transglutaminase|*]] | [[Category:Tissue transglutaminase|*]] | ||
Latest revision as of 11:35, 10 March 2015
| Exendin 4 | |
|---|---|
| Substrate peptide name | Exendin 4 |
| Synonyms | Exenatide |
| Determination type | In vitro |
| Source | Heloderma suspectum |
| Subcellular localization | Excreted |
| Swissprot ID | P26349 |
| Reactive glutamines | - |
| Reactive lysines | K12, K27 |
| Substrate sequence | TSDLSKQMEEE
FIEWLKNGGPS |
| Structure | 1JRJ |
| Surface accessibility | |
| Disorder prediction | IUPred |
| Reference | PMID:18761350 |
| Notes | It is a GIP-1 incretin mimetic having a role in the regulation of blood glucose level.
It is used in the medication of type II diabetes as Byetta (Amylin, Lilly). |
