Difference between revisions of "Hypoxia inducible factor 1"

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|-
 
| Substrate peptide name
 
| Substrate peptide name
| Hypoxia inducible factor 1 beta
+
| Hypoxia-inducible factor 1-beta
 
|-
 
|-
 
| Synonyms
 
| Synonyms
| ARNT-interacting protein
+
| Aryl hydrocarbon receptor nuclear translocator
 +
Dioxin receptor, nuclear translocator
 
|-
 
|-
 
| Determination type
 
| Determination type
|  
+
| in situ/in vitro
 
|-
 
|-
 
| Source
 
| Source
|  
+
| Homo sapiens
 
|-
 
|-
 
| Subcellular localization
 
| Subcellular localization
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|-
 
|-
 
| Swissprot ID
 
| Swissprot ID
| [http://au.expasy.org/uniprot/Q16665 Q16665]
+
| [http://au.expasy.org/uniprot/P27540 P27540]
 
|-
 
|-
 
| Interacting residues
 
| Interacting residues
|  
+
| Not determined yet
 
|-
 
|-
 
| Interacting sequence
 
| Interacting sequence
|  
+
| Not determined yet
 
|-
 
|-
 
| TG2 Swissprot ID
 
| TG2 Swissprot ID
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|-
 
|-
 
| Interacting residues of TG2
 
| Interacting residues of TG2
|  
+
| Not determined yet
 
|-
 
|-
 
| Interacting sequence of TG2
 
| Interacting sequence of TG2
|
+
| Not determined yet
 
|-
 
|-
 
| Structure
 
| Structure
| [http://www.rcsb.org/pdb/explore/explore.do?structureId=1H2M 1H2M]
+
| [http://www.rcsb.org/pdb/explore/explore.do?structureId=4EQ1 4EQ1]
 
|-
 
|-
 
| Surface accessibility
 
| Surface accessibility
|  
+
| -
 
|-
 
|-
 
| Disorder prediction
 
| Disorder prediction
| [http://iupred.enzim.hu/index.html IUPred]
+
| [http://iupred.enzim.hu IUPred]
 
|-
 
|-
 
| Reference
 
| Reference

Latest revision as of 12:25, 21 March 2017

Hypoxia inducible factor 1
Substrate peptide name Hypoxia-inducible factor 1-beta
Synonyms Aryl hydrocarbon receptor nuclear translocator

Dioxin receptor, nuclear translocator

Determination type in situ/in vitro
Source Homo sapiens
Subcellular localization Cytosol/Nucleus
Swissprot ID P27540
Interacting residues Not determined yet
Interacting sequence Not determined yet
TG2 Swissprot ID P21980
Interacting residues of TG2 Not determined yet
Interacting sequence of TG2 Not determined yet
Structure 4EQ1
Surface accessibility -
Disorder prediction IUPred
Reference PMID:18375543
Notes TG2 inhibited a HIF-dependent transcription under hypoxic conditions without affecting nuclear protein levels

for HIF1{alpha} or HIF1{beta}, their ability to form the HIF1 heterodimeric transcription factor, or HIF1 binding

to its DNA response element.