Hypoxia inducible factor 1
| Hypoxia inducible factor 1 | |
|---|---|
| Substrate peptide name | Hypoxia-inducible factor 1-beta |
| Synonyms | Aryl hydrocarbon receptor nuclear translocator
Dioxin receptor, nuclear translocator |
| Determination type | in situ/in vitro |
| Source | Homo sapiens |
| Subcellular localization | Cytosol/Nucleus |
| Swissprot ID | P27540 |
| Interacting residues | Not determined yet |
| Interacting sequence | Not determined yet |
| TG2 Swissprot ID | P21980 |
| Interacting residues of TG2 | Not determined yet |
| Interacting sequence of TG2 | Not determined yet |
| Structure | 4EQ1 |
| Surface accessibility | - |
| Disorder prediction | IUPred |
| Reference | PMID:18375543 |
| Notes | TG2 inhibited a HIF-dependent transcription under hypoxic conditions without affecting nuclear protein levels
for HIF1{alpha} or HIF1{beta}, their ability to form the HIF1 heterodimeric transcription factor, or HIF1 binding to its DNA response element. |