Hypoxia inducible factor 1

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Hypoxia inducible factor 1
Substrate peptide name Hypoxia-inducible factor 1-beta
Synonyms Aryl hydrocarbon receptor nuclear translocator

Dioxin receptor, nuclear translocator

Determination type in situ/in vitro
Source Homo sapiens
Subcellular localization Cytosol/Nucleus
Swissprot ID P27540
Interacting residues Not determined yet
Interacting sequence Not determined yet
TG2 Swissprot ID P21980
Interacting residues of TG2 Not determined yet
Interacting sequence of TG2 Not determined yet
Structure 4EQ1
Surface accessibility -
Disorder prediction IUPred
Reference PMID:18375543
Notes TG2 inhibited a HIF-dependent transcription under hypoxic conditions without affecting nuclear protein levels

for HIF1{alpha} or HIF1{beta}, their ability to form the HIF1 heterodimeric transcription factor, or HIF1 binding

to its DNA response element.